{"status":"success","code":0,"data":{"hashid":"2kqwmxnl","title":"\u9760BD\u9996\u4ed8\u5e26\u98de\u4e1a\u7ee9\uff1f\u53cc\u6297\u8d5b\u9053\u7ade\u4e89\u767d\u70ed\u5316\uff01\u4e09\u751f\u56fd\u5065\uff1a\u805a\u7126\u6e90\u5934\u521b\u65b0\u53ca\u5dee\u5f02\u5316\u7814\u53d1","subTitle":"\u9760BD\u9996\u4ed8\u5e26\u98de\u4e1a\u7ee9\uff1f\u53cc\u6297\u8d5b\u9053\u7ade\u4e89\u767d\u70ed\u5316\uff01\u4e09\u751f\u56fd\u5065\uff1a\u805a\u7126\u6e90\u5934\u521b\u65b0\u53ca\u5dee\u5f02\u5316\u7814\u53d1","cover":"https:\/\/static.timesmedia.com.cn\/fusion-platform\/a8ed4c81a3992ab206d36522fc419888\/20250916\/9ef5f224fa3540229d0ec596ca83083a.png","pageType":12,"pageUrl":"https:\/\/epaper-h5.time-weekly.com\/article?id=2kqwmxnl","summary":"\u4e1a\u7ee9\u4e0a\u6da8\u6216\u4e3b\u8981\u7531\u4e8e\u62a5\u544a\u671f\u5185\u4e0e\u8f89\u745e\u8fbe\u6210\u5408\u4f5c","createdAt":1772077163,"onlineAt":1772077162,"content":"

\u7531\u4e8e\u4e0e\u8f89\u745e\u8fbe\u6210\u5408\u4f5c\uff0c\u4e09\u751f\u56fd\u5065\uff08688336.SH\uff092025\u5e74\u4e1a\u7ee9\u5927\u6da8\u3002\u6839\u636e\u516c\u53f8\u53d1\u5e03\u7684\u4e1a\u7ee9\u5feb\u62a5\uff0c2025\u5e74\u4e09\u751f\u56fd\u5efa\u5b9e\u73b0\u8425\u4e1a\u6536\u516541.99\u4ebf\u5143\uff0c\u8f83\u4e0a\u5e74\u589e\u52a0251.81%\uff1b\u5b9e\u73b0\u5f52\u6bcd\u51c0\u5229\u6da629.39\u4ebf\u5143\uff0c\u8f83\u4e0a\u5e74\u6da8\u5e45317.09%\u3002<\/p>

\u540c\u65f6\uff0c\u6263\u9664\u672c\u5e74\u5ea6\u786e\u8ba4\u7684\u653f\u5e9c\u8865\u52a9\u6536\u76ca\u3001\u7406\u8d22\u4ea7\u54c1\u5229\u606f\u6536\u5165\u3001\u56fa\u5b9a\u8d44\u4ea7\u5904\u7f6e\u635f\u5931\u3001\u53c2\u80a1\u516c\u53f8\u5206\u7ea2\u6536\u76ca\u53ca\u8425\u4e1a\u5916\u652f\u51fa\u540e\uff0c\u5b9e\u73b0\u6263\u975e\u51c0\u5229\u6da628.05\u4ebf\u5143\uff0c\u6da8\u5e451041.01%\u3002<\/p>

\u4e09\u751f\u56fd\u5065\u5728\u4e1a\u7ee9\u5feb\u62a5\u4e2d\u6307\u51fa\uff0c\u8425\u4e1a\u603b\u6536\u5165\u3001\u5f52\u6bcd\u51c0\u5229\u6da6\u3001\u6263\u975e\u51c0\u5229\u6da6\u3001\u57fa\u672c\u6bcf\u80a1\u6536\u76ca\u3001\u603b\u8d44\u4ea7\u7b49\u6307\u6807\u76f8\u6bd4\u4e0a\u5e74\u540c\u671f\u5747\u51fa\u73b0\u8f83\u5927\u5e45\u5ea6\u589e\u957f\uff0c\u4e3b\u8981\u7531\u4e8e\u62a5\u544a\u671f\u5185\u516c\u53f8\u4e0e\u8f89\u745e\u516c\u53f8\uff08Pfizer Inc.\uff09\u8fbe\u6210\u91cd\u8981\u5408\u4f5c\uff0c\u516c\u53f8\u6536\u5230\u8f89\u745e\u516c\u53f8\u5c31707\u9879\u76ee\u652f\u4ed8\u7684\u6388\u6743\u8bb8\u53ef\u9996\u4ed8\u6b3e\u5e76\u76f8\u5e94\u786e\u8ba4\u6536\u5165\u7ea628.90\u4ebf\u5143\u3002<\/p>

2025\u5e745\u670820\u65e5\uff0c\u4e09\u751f\u56fd\u5065\u7684\u6bcd\u516c\u53f8\u4e09\u751f\u5236\u836f\uff0801530.HK\uff09\u4e0e\u8f89\u745e\u5173\u4e8ePD-1\/VEGF\u53cc\u7279\u5f02\u6027\u6297\u4f53SSGJ-707\u7684\u4ea4\u6613\u53d1\u5e03\uff0c\u6b64\u6b21\u4ea4\u6613\u8fbe\u621012.5\u4ebf\u7f8e\u5143\u4e0d\u53ef\u9000\u8fd8\u4e14\u4e0d\u53ef\u62b5\u6263\u7684\u9996\u4ed8\u6b3e\u3002<\/p>

\u5728\u8fbe\u6210\u91cd\u78c5\u4ea4\u6613\u7684\u540c\u65f6\uff0c\u4e09\u751f\u56fd\u5065\u6216\u5c06\u9762\u4e34PD-1\/VEGF\u53cc\u6297\u8d5b\u9053\u65e5\u8d8b\u6fc0\u70c8\u7684\u5e02\u573a\u7ade\u4e89\u3002\u4f5c\u4e3a\u8fd1\u5e74\u6765\u5907\u53d7\u77a9\u76ee\u7684\u660e\u661f\u9776\u70b9\uff0c\u8be5\u8d5b\u9053\u5165\u5c40\u8005\u4f17\u591a\u3001\u7ade\u4e89\u6fc0\u70c8\u3002<\/p>

Insight\u6570\u636e\u5e93\u663e\u793a\uff0c\u76ee\u524d\u5728PD-(L)1\/VEGF\u53cc\u6297\u8d5b\u9053\u4e2d\uff0c\u5eb7\u65b9\u751f\u7269\uff0809926.HK\uff09\u7814\u53d1\u7684\u4f9d\u6c83\u897f\u5355\u6297\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c\u6b64\u5916\uff0cBMS\/BioNTech\u7684PM8002\u3001\u795e\u5dde\u7ec6\u80de\uff08688520.SH\uff09\u7684SCTB14\u3001\u534e\u6d77\u836f\u4e1a\uff08600521.SH\uff09\u5b50\u516c\u53f8\u534e\u5965\u6cf0\u7684HB0025\u5747\u5df2\u8fdb\u5165\u4e34\u5e8aIII\u671f\u3002<\/p>

\u9488\u5bf9\u5982\u4f55\u5e94\u5bf9PD-(L)1\/VEGF\u53cc\u6297\u8d5b\u9053\u7684\u6fc0\u70c8\u7ade\u4e89\u76f8\u5173\u95ee\u9898\uff0c\u4e09\u751f\u56fd\u5065\u65b9\u9762\u5411\u65f6\u4ee3\u5468\u62a5\u8bb0\u8005\u8868\u793a\uff0c\u672a\u6765\u516c\u53f8\u5c06\u66f4\u52a0\u805a\u7126\u4e8e\u6838\u5fc3\u7ba1\u7ebf\u7684\u6e90\u5934\u521b\u65b0\u548c\u5dee\u5f02\u5316\u7814\u53d1\uff0c\u6301\u7eed\u63d0\u5347\u957f\u671f\u4ef7\u503c\u3002<\/p>

\n \n \u56fe\u7247\u6765\u6e90\uff1a\u56fe\u866b\u521b\u610f<\/span>\n <\/p>

\u660e\u661f\u53cc\u6297\u8d5b\u9053\u7ade\u4e89\u6fc0\u70c8<\/p>

2025\u5e745\u670820\u65e5\uff0c\u4e09\u751f\u5236\u836f\u5ba3\u5e03\uff0c\u4e0e\u8f89\u745e\u7b7e\u7f72\u534f\u8bae\uff0c\u5c06\u5411\u8f89\u745e\u72ec\u5bb6\u6388\u4e88\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684PD-1\/VEGF\u53cc\u7279\u5f02\u6027\u6297\u4f53SSGJ-707\u5728\u5168\u7403\uff08\u4e0d\u5305\u62ec\u4e2d\u56fd\u5185\u5730\uff09\u7684\u5f00\u53d1\u3001\u751f\u4ea7\u3001\u5546\u4e1a\u5316\u6743\u5229\u3002\u6839\u636e\u534f\u8bae\uff0c\u4e09\u751f\u5236\u836f\u5c06\u83b7\u5f9712.5\u4ebf\u7f8e\u5143\u4e0d\u53ef\u9000\u8fd8\u4e14\u4e0d\u53ef\u62b5\u6263\u7684\u9996\u4ed8\u6b3e\uff0c\u4ee5\u53ca\u6700\u9ad8\u53ef\u8fbe48\u4ebf\u7f8e\u5143\u7684\u5f00\u53d1\u3001\u76d1\u7ba1\u6279\u51c6\u548c\u9500\u552e\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002<\/p>

\u4f34\u968f\u8be5\u4ea4\u6613\u7684\u516c\u5e03\uff0c\u4e09\u751f\u56fd\u5065\u80a1\u4ef7\u57282025\u5e745\u670819\u65e5-5\u670822\u65e5\u8fde\u7eed4\u65e5\u6da8\u505c\uff0c\u5e76\u4e00\u5ea6\u5e26\u52a8\u8d77\u6574\u4e2a\u521b\u65b0\u836f\u677f\u5757\u7684\u725b\u5e02\u884c\u60c5\u3002\u8be5\u4ea4\u6613\u6240\u5e26\u6765\u7684\u4ed8\u6b3e\u4e5f\u6210\u4e3a\u4e09\u751f\u56fd\u50652025\u5e74\u4e1a\u7ee9\u5927\u5e45\u589e\u957f\u7684\u4e3b\u8981\u539f\u56e0\u3002<\/p>

\u6b64\u6b21\u4ea4\u6613\u7684\u540e\u7eed\u4ed8\u6b3e\u60c5\u51b5\u4e5f\u6210\u4e3a\u5e02\u573a\u5173\u5fc3\u7684\u95ee\u9898\uff0c2026\u5e742\u67086\u65e5\uff0c\u4e09\u751f\u56fd\u5065\u5728\u4e92\u52a8\u5e73\u53f0\u56de\u590d\u79f0\uff0c\u516c\u53f8\u6536\u5230\u9996\u4ed8\u6b3e\u4e4b\u540e\uff0c\u8f89\u745e\u5e94\u6309\u7167\u8bb8\u53ef\u4ea7\u54c1\u4e8e\u8bb8\u53ef\u533a\u57df\u7684\u5e74\u5ea6\u51c0\u9500\u552e\u989d\u6309\u7ea6\u5b9a\u7684\u53cc\u4f4d\u6570\u7684\u68af\u5ea6\u6bd4\u4f8b\u5411\u8bb8\u53ef\u65b9\u652f\u4ed8\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u3002\u6309\u7167\u7ea6\u5b9a\u5206\u914d\u6bd4\u4f8b\uff0c\u4e09\u751f\u56fd\u5065\u53ef\u4ee5\u5206\u914d30%\u3002<\/p>

\u4e09\u751f\u56fd\u5065\u5728\u56de\u590d\u4e2d\u4e5f\u8868\u793a\uff0c\u4e09\u751f\u56fd\u5065\u3001\u4e09\u751f\u5236\u836f\u548c\u6c88\u9633\u4e09\u751f\u5b9e\u9645\u6536\u53d6\u7684\u5f00\u53d1\u91cc\u7a0b\u7891\u6b3e\u9879\u548c\u76d1\u7ba1\u91cc\u7a0b\u7891\u6b3e\u9879\uff0c\u987b\u6839\u636e\u76f8\u5e94\u6761\u4ef6\u53ca\/\u6216\u65f6\u95f4\u8282\u70b9\u7684\u8fbe\u6210\u548c\u7ea6\u5b9a\u6267\u884c\uff0c\u5b58\u5728\u4e0d\u786e\u5b9a\u6027\u3002\u4e8e\u672c\u6b21\u4ea4\u6613\u4e2d\u6240\u7ea6\u5b9a\u7684\u9500\u552e\u91cc\u7a0b\u7891\u6b3e\u9879\u548c\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u7684\u652f\u4ed8\uff0c\u987b\u4ee5\u7ea6\u5b9a\u7684\u9500\u552e\u8fbe\u6210\u60c5\u51b5\u4f5c\u4e3a\u89e6\u53d1\u6761\u4ef6\u3002\u8bb8\u53ef\u4ea7\u54c1\u4e0a\u5e02\u540e\u7684\u9500\u552e\u60c5\u51b5\u53ef\u80fd\u53d7\u5230\u7528\u836f\u9700\u6c42\u3001\u5e02\u573a\u7ade\u4e89\u3001\u9500\u552e\u6e20\u9053\u7b49\u56e0\u7d20\u5f71\u54cd\uff0c\u5b58\u5728\u4e0d\u786e\u5b9a\u6027\u3002<\/p>

PD-(L)1\/VEGF\u53cc\u6297\u662f\u5f53\u524d\u5e7f\u53d7\u5e02\u573a\u5173\u6ce8\u7684\u660e\u661f\u9776\u70b9\uff0c\u636e\u533b\u836f\u9b54\u65b9\u6570\u636e\u5e93\uff0c\u622a\u81f3\u76ee\u524d\uff0c\u5168\u7403\u5171\u670917\u6b3ePD-(L)1\/VEGF\u53cc\u6297\u836f\u7269\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\uff0c\u4e14\u5747\u4e0e\u4e2d\u56fd\u521b\u65b0\u836f\u4f01\u76f8\u5173\u3002<\/p>

\u57282024\u5e74\u4e16\u754c\u80ba\u764c\u5927\u4f1a\uff08WCLC\uff09\u4e2d\uff0c\u5eb7\u65b9\u751f\u7269PD-1\/VEGF\u53cc\u6297\u4f9d\u6c83\u897f\uff08AK112\uff09\u901a\u8fc7\u201c\u5934\u5bf9\u5934\u201d\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u5c55\u73b0\u51fa\u8d85\u8fc7\u9ed8\u6c99\u4e1cK\u836f\u7684\u6f5c\u529b\u540e\uff0cPD-1\/VEGF\u53cc\u6297\u4e00\u6218\u6210\u540d\uff0c\u5438\u5f15\u5404\u5927\u836f\u4f01\u7ade\u76f8\u5165\u5c40\uff0c\u6210\u4e3a\u7ade\u4e89\u6fc0\u70c8\u7684\u660e\u661f\u9776\u70b9\u3002<\/p>

\u9664\u4e09\u751f\u56fd\u5065\u4e0e\u8f89\u745e\u7684\u4ea4\u6613\u5916\uff0cPD-(L)1\/VEGF\u53cc\u6297\u9886\u57df\u8fd1\u4e24\u5e74\u91cd\u78c5BD\u4ea4\u6613\u4e0d\u65ad\u3002\u5982\u57282026\u5e741\u670812\u65e5\uff0c\u8363\u660c\u751f\u7269\uff08688331.SH\uff1b09995.HK\uff09\u4e0e\u827e\u4f2f\u7ef4\u5c31\u8363\u660c\u751f\u7269\u7684PD-1\/VEGF\u53cc\u6297\u836f\u7269RC148\u7b7e\u7f72\u72ec\u5bb6\u6388\u6743\u8bb8\u53ef\u534f\u8bae\u3002\u8be5\u4ea4\u6613\u7684\u9996\u4ed8\u6b3e\u4e3a6.5\u4ebf\u7f8e\u5143\uff0c\u8363\u660c\u751f\u7269\u6709\u8d44\u683c\u83b7\u5f97\u6700\u9ad8\u8fbe49.5\u4ebf\u7f8e\u5143\u7684\u5f00\u53d1\u3001\u76d1\u7ba1\u548c\u5546\u4e1a\u5316\u91cc\u7a0b\u7891\u4ed8\u6b3e\u7b49\u3002<\/p>

2025\u5e746\u67082\u65e5\uff0c\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\uff08BMS\uff09\u5ba3\u5e03\u4e0eBioNTech\u8fbe\u6210\u534f\u8bae\uff0c\u5171\u540c\u5f00\u53d1\u548c\u5546\u4e1a\u5316BNT327\uff08PM8002\uff09\uff0cBMS\u5c06\u5411BioNTech\u652f\u4ed8\u9ad8\u8fbe111\u4ebf\u7f8e\u5143\u7684\u91cc\u7a0b\u7891\u4ed8\u6b3e\u30022024\u5e7411\u6708\uff0cBioNTech\u4ee59.5\u4ebf\u7f8e\u5143\u6536\u8d2d\u4e2d\u56fd\u4f01\u4e1a\u666e\u7c73\u65af\u751f\u7269\uff0c\u83b7\u5f97PD-L1\/VEGF\u53cc\u6297BNT327\u7684\u5168\u7403\u6743\u76ca\u3002<\/p>

PD-L1\/VEGF\u53cc\u6297\u88ab\u4e1a\u7ee9\u5bc4\u4e88\u539a\u671b\uff0c\u4f46\u8be5\u8d5b\u9053\u4e5f\u5e76\u975e\u4e00\u76f4\u4e50\u89c2\u30022025\u5e749\u67087\u65e5\uff0c\u5eb7\u65b9\u751f\u7269\u5408\u4f5c\u4f19\u4f34Summit\u5728WCLC\u4e0a\u516c\u5e03\u5176PD-1\/VEGF\u53cc\u6297AK112\u5168\u7403\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8cHARMONi\u7684\u66f4\u65b0\u6570\u636e\uff0c\u5176\u4e2d\u8fbe\u5230\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u7684\u4e3b\u8981\u7ec8\u70b9\uff0c\u4f46\u603b\u751f\u5b58\u671f\uff08OS\uff09\u672a\u8fbe\u5230\u7edf\u8ba1\u5b66\u663e\u8457\u5dee\u5f02\u3002\u8be5\u7ed3\u679c\u516c\u5e03\u540e\u5eb7\u65b9\u751f\u7269\u80a1\u4ef7\u5927\u8dcc\uff0c\u4e5f\u5f71\u54cd\u4e1a\u754c\u5bf9PD-1\/VEGF\u53cc\u6297\u8d5b\u9053\u7684\u4fe1\u5fc3\u3002<\/p>

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